Broadband NIRS

Definition: Broadband NIRS (bNIRS) is an optical imaging technique that measures in-vivo changes in tissue hemodynamics (oxyhemoglobin and deoxyhemoglobin) and, often, other biomarkers such as metabolism (e.g., redox state of cytochrome-c-oxidase or (oxCCO)). Tissue light attenuation measurements are performed at a larger number of wavelengths than typical 2-4 wavelength NIRS instruments, e.g., spanning 600 to 1000 nm at 1 nm wavelength resolution, to reduce crosstalk effects and noise.In contrast to fNIRS systems, bNIRS use broadband light sources, for example, a tungsten halogen light source emitting light between 200 – 2500 nm and a wavelength-dependent detector (e.g., a spectrophotometer). Optical filters may be placed in the source or detector optical path to narrow the spectrum to the region of interest.

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References: https://doi.org/10.1117/1.JBO.21.9.091307

Related terms: multi-wavelength fNIRS

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