Coherent Hemodynamics Spectroscopy

Definition: Coherent Hemodynamics Spectroscopy (CHS) is a method for collecting physiological information from the local cerebral response to systemic blood pressure changes or functional activation. CHS is based on the analysis of cerebral hemodynamic oscillations that are either induced or occur spontaneously at multiple frequencies, and that are measured with NIRS. Data are analyzed using a hemodynamic model, which enables extraction of physiological information, including blood transit times in the microvasculature and the autoregulation cutoff frequency. CHS is particularly promising for clinical applications in populations that show impairment in these functions, e.g. diabetes, Parkinson’s disease, and stroke. Definition: Coherent Hemodynamics Spectroscopy (CHS) is a method for collecting physiological information from the local cerebral response to systemic blood pressure changes or functional activation. CHS is based on the analysis of cerebral hemodynamic oscillations that are either induced or occur spontaneously at multiple frequencies, and that are measured with NIRS. Data are analyzed using a hemodynamic model, which enables extraction of physiological information, including blood transit times in the microvasculature and the autoregulation cutoff frequency. CHS is particularly promising for clinical applications in populations that show impairment in these functions, e.g. diabetes, Parkinson’s disease, and stroke.

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