Cerebral Tissue Oxygenation Saturation

Definition: Cerebral tissue oxygenation saturation (SctO2) is a measurement of the level of oxygen saturation in the cerebral tissue of the brain. It is typically expressed as a percentage and can be obtained by some approaches with near-infrared spectroscopy (NIRS) technology. SctO2 reflects the proportion of hemoglobin molecules in the cortical blood vessels that are bound to oxygen, and it provides valuable information about the oxygen supply to the brain. Monitoring SctO2 is important in various clinical settings, including critical care, surgery, and neonatology, as changes in SctO2 can indicate conditions such as cerebral hypoxia, ischemia, and reperfusion injury, which require prompt clinical interventions to improve brain perfusion and oxygenation.

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References: https://doi.org/10.1088/0031-9155/48/15/311

https://doi.org/10.1016/j.neuroimage.2012.01.040

https://doi.org/10.1016/j.neuroimage.2004.07.013

https://doi.org/10.1016/j.neuroimage.2023.120189

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