Functional connectivity

Definition: Functional connectivity (FC) is defined as the statistical dependency between two or more time series originating from different brain regions. FC analyses are mostly conducted to investigate how neural activity is correlated in time between brain regions or networks. FC can be calculated during different states (e.g., during rest or during performance of a task). In task-related contexts, it is important to consider the effect of task-related activity in resulting FC measures, as an external signal or stimulus can result in similar temporal profiles of FC across regions without these regions being connected per se. Definition: Functional connectivity (FC) is defined as the statistical dependency between two or more time series originating from different brain regions. FC analyses are mostly conducted to investigate how neural activity is correlated in time between brain regions or networks. FC can be calculated during different states (e.g., during rest or during performance of a task). In task-related contexts, it is important to consider the effect of task-related activity in resulting FC measures, as an external signal or stimulus can result in similar temporal profiles of FC across regions without these regions being connected per se.

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References: https://doi.org/10.1016/j.neuroimage.2018.01.053

Related terms: Resting-state functional connectivity (rsFC), Task-state functional connectivity (tsFC), resting state networks (RSN), dynamic functional connectivity, connectivity  

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