Optical topography

Definition: Methods which produce two-dimensional (2D) images of a plane parallel to the sources and detectors with limited depth information. It refers to imaging a few centimeters of tissue (the separation between source and detector is generally < 4 cm). The typical application is imaging haemodynamic changes in the cortex of the brain, where we are interested in imaging a change in optical properties with a time course of a few seconds. Such systems generally employ continuous-wave instrumentation with laser diode sources modulated at a few kilohertz and lock-in detectors. Images are usually reconstructed using a linear approach and presented as a two-dimensional slice parallel to the plane of sources and detectors. Definition: Methods which produce two-dimensional (2D) images of a plane parallel to the sources and detectors with limited depth information. It refers to imaging a few centimeters of tissue (the separation between source and detector is generally < 4 cm). The typical application is imaging haemodynamic changes in the cortex of the brain, where we are interested in imaging a change in optical properties with a time course of a few seconds. Such systems generally employ continuous-wave instrumentation with laser diode sources modulated at a few kilohertz and lock-in detectors. Images are usually reconstructed using a linear approach and presented as a two-dimensional slice parallel to the plane of sources and detectors.

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Related terms: Functional Near Infrared Spectroscopy, Diffuse Optical Tomography  

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