Cerebral blood volume

Definition: Cerebral blood volume is the total amount of blood in the brain. It is usually expressed in of tissue. The total hemoglobin () is related to cerebral blood volume by cerebral haematocrit by: Where: is the brain density. is the molecular weight of the hemoglobin. is the large vessel hemodynamic concentration. is the cerebral to large vessels hematocrit ratio. If the hematocrit is considered to remain constant during hemodynamic response to activation, then is proportional to cerebral blood volume. CBV is a critical physiological indicator of tissue viability and vascular reactivity as CBV changes are directly linked to the regulation of cerebral blood flow under pathophysiological conditions

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References:

https://doi.org/10.1016/j.neuroimage.2004.07.013

https://doi.org/10.1161/01.str.5.5.630

https://doi.org/10.1152/jappl.1990.68.3.1086

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