Near infrared spectroscopy

Definition: Near-infrared spectroscopy (NIRS) is an analytical optical technique that uses near-infrared light (650 – 900 nm) to shine light to a sample and measures the portion of the light that travels through the sample. NIRS has been used in many fields such as agriculture, food, chemical industries, clinical chemistry, pharmaceutical, and medicine. Absorption and/or fluorescence NIRS is utilized in different techniques with different resolution and penetration depth, such as conventional microscopy, confocal/multi-photon microscopy, optical coherence tomography, photodynamic therapy, in vivo molecular imaging and medical diffuse optical imaging. The main applications in medicine are pulse oximetry, brain/muscle oximetry, functional NIRS and optical mammography.Frans Jöbsis is considered the founder of in vivo medical NIRS that enables real-time non-invasive detection of regional hemoglobin oxygenation.

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Related terms: functional Near Infrared Spectroscopy  

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